![Oxycodone Hydrochloride Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive and It is usually taken by mouth, and is available in immediate-release and controlled-release formulations. Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation. In the United Kingdom, it is available by injection. Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin. Medical uses Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient. It may improve quality of life in certain types of pain. Numerous studies have been completed, and the appropriate use of this compound does improve the quality of life of patients with long term chronic pain syndromes. Oxycodone is available as a controlled-release tablet, intended to be taken every 12 hours. A 2006 review found that controlled-release oxycodone is comparable to immediate-release oxycodone, morphine, and hydromorphone in management of moderate to severe cancer pain, with fewer side effects than morphine. The author concluded that the controlled-release form is a valid alternative to morphine and a first-line treatment for cancer pain. In 2014, the European Association for Palliative Care recommended oxycodone by mouth as a second-line alternative to morphine by mouth for cancer pain. Available forms See also: Oxycodone/paracetamol, Oxycodone/aspirin, Oxycodone/ibuprofen, and Oxycodone/naloxone Both sides of a single 10mg OxyContin pill. Oxycodone is available in a variety of formulations for by mouth or under the tongue: Immediate-release oxycodone (OxyFast, OxyIR, OxyNorm, Roxicodone) Controlled-release oxycodone (OxyContin, Xtampza ER) – 10–12 hour duration Oxycodone tamper-resistant (OxyContin OTR) Immediate-release oxycodone with paracetamol (acetaminophen) (Percocet, Endocet, Roxicet, Tylox) Immediate-release oxycodone with aspirin (Endodan, Oxycodan, Percodan, Roxiprin) Immediate-release oxycodone with ibuprofen (Combunox) Controlled-release oxycodone with naloxone (Targin, Targiniq, Targinact)[38] – 10–12 hour duration Controlled-release oxycodone with naltrexone (Troxyca) – 10–12 hour duration A liquid solution containing 10mg of oxycodone per 1ml In the US, oxycodone is only approved for use by mouth, available as tablets and oral solutions. Parenteral formulations of oxycodone (brand name OxyNorm) are also available in other parts of the world, however, and are widely used in the European Union. In Spain, the Netherlands and the United Kingdom, oxycodone is approved for intravenous (IV) and intramuscular (IM) use. When first introduced in Germany during World War I, both IV and IM administrations of oxycodone were commonly used for postoperative pain management of Central Powers soldiers. Oxycodone, like other opioid analgesics, tends to induce feelings of euphoria, relaxation and reduced anxiety in those who are occasional users. These effects make it one of the most commonly abused pharmaceutical drugs in the United States. The abuse of Oxycodone, as well as related opioids more broadly, is not unique to the United States and is a common drug of abuse globally. Uses for Oxycodone Acute Pain Relief of moderate to severe pain when use of an opiate analgesic is appropriate and alternative treatments are inadequate. Usually, temporary relief of moderate to moderately severe pain such as that associated with acute and some chronic medical disorders including renal or biliary colic, acute trauma, postoperative pain, and cancer. Opiates given orally in combination with acetaminophen or NSAIAs may produce greater analgesic effect than either drug alone; may also cause fewer adverse effects than equianalgesic doses of the individual drugs alone. Extended-release oxycodone hydrochloride/acetaminophen in fixed combination: Relief of acute pain that is severe enough to require opiate therapy and for which alternative treatments (e.g., nonopiate analgesics) are inadequate or not tolerated. In symptomatic treatment of acute pain, reserve opiate analgesics for pain resulting from severe injuries, severe medical conditions, or surgical procedures, or when nonopiate alternatives for relieving pain and restoring function are expected to be ineffective or are contraindicated. Use smallest effective dosage for shortest possible duration since long-term opiate use often begins with treatment of acute pain. Optimize concomitant use of other appropriate therapies. (See Managing Opiate Therapy for Acute Pain under Dosage and Administration.) Reserve oxycodone hydrochloride extended-release tablets and oxycodone myristate extended-release capsules for relief of pain that is severe enough to require long-term, daily, around-the-clock use of an opiate analgesic and for which alternative treatment options (e.g., nonopiate analgesics or immediate-release opiates) are inadequate or not tolerated; not indicated for as-needed (“prn”) use. Chronic Pain For relief of moderate to severe malignant (cancer) pain and chronic nonmalignant pain when use of an opiate analgesic is appropriate and alternative treatments are inadequate. Oxycodone hydrochloride extended-release tablets and oxycodone myristate extended-release capsules: Use only for relief of pain that is severe enough to require long-term, daily, around-the-clock use of an opiate analgesic and for which alternative treatment options (e.g., nonopiate analgesics, immediate-release opiates) are inadequate or not tolerated. Not indicated for as-needed (“prn”) use. In the management of chronic pain associated with a terminal illness such as cancer, the principal goal of analgesic therapy is to make the patient relatively pain-free while maintaining as good a quality of life as possible. Oxycodone Hydrochloride Extended-release Tablets Swallow tablets whole; do not break, cut, dissolve, crush, or chew. (See Respiratory Depression in Boxed Warning.) Oxycodone Generic name: oxycodone [ ox-i-KOE-done ] Brand names: Oxaydo, OxyContin, Oxyfast, Roxicodone, RoxyBond, Xtampza ER; oxycodone is also present in the following combination drugs: Combunox, Endocet, Endodan, Moxduo, Oxycodan, Percocet, Percodan, Primlev, Roxicet, Xartemis XR, and others Oxycodone -Brand names: Oxycontin, Oxypro, Longtec, Reltebon, Zomestine](https://ghsplean.com/wp-content/uploads/2024/09/Picsart_24-09-18_21-03-34-475.jpg)
Oxycodone Hydrochloride
Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive and It is usually taken by mouth, and is available in immediate-release and controlled-release formulations. Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation. In the United Kingdom, it is available by injection. Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin.
Medical uses
Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient. It may improve quality of life in certain types of pain. Numerous studies have been completed, and the appropriate use of this compound does improve the quality of life of patients with long term chronic pain syndromes.
![Tris Promethazine Hydrochloride and Codeine Phosphate Oral Solution Each 5ml (One Teaspoonful) contains: Promethazine Hydrochloride, USP.......... 6.25 mg Codeine Phosphate, USP..................... 10 mg Alcohol................................. 8.0% v/v USUAL DOSAGE:See accompanying package insert. WARNINGS:KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN. In case of accidental overdose,seek professional assistance or contact a Poison Control Center immediately. Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature] KEEP TIGHTLY CLOSED , PROTECT FROM LIGHT. Dispense in a tight, light-resistant container as defined in the USP, with child resistant closure. Tris Promethazine & Codeine Phosphate Oral Solution is an opioid pain reliever which is used to treat mild to moderately severe pain and to help reduce coughing. Codeine is available as a single ingredient tablet and also available in multi ingredients products combined with other pain relieving medicines or cold and flu medicines. Codeine and promethazine is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine and promethazine contains an opioid (narcotic) cough medicine, and may be habit-forming. Manufactured by: Tris Pharma,Inc. Monmouth Junction,NJ 08852](https://ghsplean.com/wp-content/uploads/2023/12/Picsart_23-12-07_21-25-53-217-360x480.jpg)
![Tris Promethazine Hydrochloride and Codeine Phosphate Oral Solution Each 5ml (One Teaspoonful) contains: Promethazine Hydrochloride, USP.......... 6.25 mg Codeine Phosphate, USP..................... 10 mg Alcohol................................. 8.0% v/v USUAL DOSAGE:See accompanying package insert. WARNINGS:KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN. In case of accidental overdose,seek professional assistance or contact a Poison Control Center immediately. Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature] KEEP TIGHTLY CLOSED , PROTECT FROM LIGHT. Dispense in a tight, light-resistant container as defined in the USP, with child resistant closure. Tris Promethazine & Codeine Phosphate Oral Solution is an opioid pain reliever which is used to treat mild to moderately severe pain and to help reduce coughing. Codeine is available as a single ingredient tablet and also available in multi ingredients products combined with other pain relieving medicines or cold and flu medicines. Codeine and promethazine is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine and promethazine contains an opioid (narcotic) cough medicine, and may be habit-forming. Manufactured by: Tris Pharma,Inc. Monmouth Junction,NJ 08852](https://ghsplean.com/wp-content/uploads/2023/12/Picsart_23-12-07_21-59-07-215-360x480.jpg)
![Nostrum Promethazine Hydrochloride Oral Solution Each 5ml (Teaspoonful) contains: Promethazine Hydrochloride, USP.......... 6.25 mg Alcohol................................. 7.0% v/v USUAL DOSAGE:See accompanying package insert. WARNINGS:KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN. In case of accidental overdose,seek professional assistance or contact a Poison Control Center immediately. Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature] KEEP TIGHTLY CLOSED , PROTECT FROM LIGHT. Dispense in a tight, light-resistant container as defined in the USP, with child resistant closure. NOSTRUM PHARMACEUTICALS LLC Company Profile | West Caldwell, NJ | Competitors, Financials & Contacts - Dun & Bradstreet. NOSTRUM Promethazine & Codeine Phosphate Oral Solution is an opioid pain reliever which is used to treat mild to moderately severe pain and to help reduce coughing. Codeine is available as a single ingredient tablet and also available in multi ingredients products combined with other pain relieving medicines or cold and flu medicines. Codeine and promethazine is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Codeine and promethazine contains an opioid (narcotic) cough medicine, and may be habit-forming.](https://ghsplean.com/wp-content/uploads/2023/12/Picsart_23-12-10_05-07-16-818-360x480.jpg)
