TUZISTRA XR (two-zis-tra) is a prescription medicine used to treat cough and respiratory symptoms that you can have with allergies or a common cold. TUZISTRA XR contains 2 medicines, codeine and chlorpheniramine. Codeine is a narcotic cough suppressant. Chlorpheniramine is an antihistamine.
Promethazine with codeine is a combination medication containing a phenothiazine and an opioid. It’s used to treat cough and nasal symptoms caused by respiratory infections or allergies in adults.
Promethazine with codeine comes as an oral solution that’s taken by mouth every 4 to 6 hours. It’s meant for short-term use only because it can be habit-forming. Possible side effects of this medication include sleepiness, dizziness, and dry mouth. Avoid drinking alcohol while taking promethazine with codeine because doing so can result in slowed breathing, a dangerous interaction.
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